Hi

I am looking for hosting software that can host domains across multiple servers - Split mail, DNS, DB and webservers but can be managed from one interface - when I create a domain it should be created on all servers.

Does anyone know of such software?

hsphere might meet your requirements,
It is java written and support multiple server mail, database, dns, web and it supports both unix and windows as well with just one interface,

checkout on http://www.psoft.net